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Some women are turning to diabetes and weight loss medications like Ozempic to help manage symptoms of polycystic ovary syndrome (PCOS), including insulin resistance. The exact cause of PCOS is unknown. "It likely is caused by a combination of genetics and environmental factors," said Kyle Graham, M.D., a board-certified OBGYN and medical director at Obstetrics and Gynecology of San Jose, part of Pediatrix® Medical Group. "At the level of the ovary, there is abnormal development of the ovarian follicles during a woman's monthly cycle,” said Dr. Graham. “When the hormones from the ovary are imbalanced monthly, the hormones around the entire body can be imbalanced." While PCOS can affect fertility, it is not advisable to take these medications if you’re trying to conceive or already pregnant. "It's contraindicated in pregnancy," noted Dr. Graham. "If you are trying to get pregnant, you should also not take semaglutide. In fact, you should stop semaglutide two months before trying to get pregnant."
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